Buckinghamshire Fire and Rescue have confirmed that a car has crashed into a car transporter this afternoon.
Buckinghamshire Fire and Rescue said that: "Crews have been called to a report of a collision involving a car and a lorry in Buckingham Road, Aylesbury
"Emergency services will be there for a considerable time."
Thames Valley police have released a statement: "The A413 is closed in both directions between Aylesbury and Whitchurch due to a serious collision. Please use an alternative route."
More on this as we get it.