Cancer Research UK announces closure of Aylesbury store as part of reshaping of retail operations
Cancer Research UK has announced the closure of more than 150 stores across the country, including one in Aylesbury, as part of the reshaping of its retail operations.
The closure of the stores is set to take place in two phases, with around 90 scheduled this month, followed by a further 100 before April 2027.


Cancer Research UK has not confirmed dates for the closures of individual stores, however the store located in the High Street, Aylesbury, is on the list.
The charity said the changes were in response to the ‘changing external and retail landscape’ and would see the reduction of its core high street chain to around 320 shops.
However, it is set to expand its network of out-of-town superstores, with 12 new ones set to open over the next two years.
The charity acknowledged the closures were ‘difficult’ but added they were ‘necessary to ensure we spend more on life-saving cancer research.’
Director of trading at Cancer Research UK Julie Byard said: “We are deeply grateful to our staff, volunteers and customers who have supported our shops over the years.
“Their dedication and generosity has helped fund vital cancer research and made a real difference to people affected by cancer.
“We know the news will be difficult, and we want to thank everyone for the incredible contribution they’ve made to our mission.
“Like many high street retailers, we’re facing rising costs and changing shopping habits. To continue funding life-saving research at the scale that’s needed, we need to change.
“The decision to close some of our shops is part of a change to our retail chain - one that will help ensure we maximise the money we raise for life-saving cancer research.
“If we don’t act now, many of our shops are likely to become financially unsustainable over the next five years.
“The decision is not a reflection of the outstanding work of our local teams. It’s a necessary step to ensure Cancer Research UK remains resilient and focused on the future.
“We are working closely with everyone impacted and will support them through this change.
“While these shops may be closing, our commitment to beating cancer together remains stronger than ever.”