Tess Finch-Lees, from Long Crendon and Dr Tracey Carter, from Oakley, won the honour for anti-discrimination work and helping disadvantaged people get into business respectively.
They both attended the lunch on Monday, October 16 at the Millenium Mayfair Hotel in London alongside 450 other women from across 40 different professions. Key note speaker was entrepreneur Martha Lane Fox.
Ms Finch-Lees is director of The Global Effectiveness Group, an organisation which helps multi-national companies integrate with different cultures and prevent bullying and prejudice in the work-place.
She has had a number of anti-discrimination articles published in national newspapers and has featured on radio and ITN news.
Recently she decided to boycott Tesco because of what she said was the Aylesbury Tring Road store's 'refusal' to prevent able-bodied drivers parking in disabled spaces. She has also campaigned for more media coverage of the Sudan crisis and helped to organise the successful International Day for Dafur in September.
And Ms Finch-Lees, who dedicated the award to her mother who is battling cancer, said the fight was still on-going in the quest to make women equal in society.
Dr Carter, 31, said she was 'amazed' when she found out she had received the accolade.
In 2005 she set up Communities in Business (CiB), a not-for-profit organisation which provides business training to people who can't generally access it, such as full-time carers and disabled people.
Dr Carter, who has a first-class degree in Human Biology and a PhD in breast cancer research, said: "Awards like Women of the Year are absolutely necessary.
"The women that have been recognised are everyday people being rewarded for what they do and I think that is fantastic."